GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2243480 | 1 | rs34560516 | chr7:65404092 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 5.29 | 7.77E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs34577383 | chr7:65385726 | CCT6P1 | chr7:65216092-65228661:+ | 0.67 | 4.9 | 3.88E-6 | Diabetic kidney disease |
| THYM | cis | rs1577917 | 1 | rs34581302 | chr6:86705948 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs34622557 | chr6:86630852 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs7246967 | 1 | rs34629498 | chr19:23060720 | ZNF492 | chr19:22817126-22850472:+ | -0.52 | -5.7 | 1.32E-7 | Bronchopulmonary dysplasia |
| THYM | cis | rs2243480 | 1 | rs34637256 | chr7:65360131 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 4.84 | 4.96E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs34702770 | chr7:65344823 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 4.84 | 4.96E-6 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs34703416 | chr7:65300642 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 4.87 | 4.36E-6 | Diabetic kidney disease |
| THYM | cis | rs9475752 | 1 | rs34812189 | chr6:56806727 | BEND6 | chr6:56819773-56892138:+ | -0.53 | -4.93 | 3.45E-6 | Menarche (age at onset) |
| THYM | cis | rs2243480 | 1 | rs34815098 | chr7:65292254 | CCT6P1 | chr7:65216092-65228661:+ | 0.64 | 4.78 | 6.3E-6 | Diabetic kidney disease |
| THYM | cis | rs1577917 | 1 | rs34852683 | chr6:86702330 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs911119 | 1 | rs34897231 | chr20:23620268 | CST9 | chr20:23583049-23586610:- | -0.48 | -4.46 | 2.25E-5 | Chronic kidney disease |
| THYM | cis | rs4663866 | 1 | rs34897410 | chr2:239182123 | LOC151174 | chr2:239133754-239140318:- | 0.89 | 4.51 | 1.84E-5 | Irritable bowel syndrome |
| THYM | cis | rs2243480 | 1 | rs34933526 | chr7:65383199 | CCT6P1 | chr7:65216092-65228661:+ | 0.68 | 4.97 | 3.0E-6 | Diabetic kidney disease |
| THYM | cis | rs56775891 | 1 | rs34945223 | chr18:77575871 | KCNG2 | chr18:77623668-77659815:+ | 0.55 | 4.38 | 3.1E-5 | Schizophrenia |